Patients should discuss resuming anticoagulant therapy (Pradaxa) after taking Praxbind with their doctors in order to keep their underlying disease under control.
Patients need to be informed of signs and symptoms of allergic hypersensitivity reactions that may be experienced during or after injection of Praxbind.Īre there any special precautions patients should be aware of before starting treatment?.Get immediate medical attention if any signs or symptoms of bleeding occur.
What should patients be aware of after treatment with Praxbind? Patients should check with their physician about any side effects that continue or are bothersome. Other side effects do not require medical attention and may go away during treatment. Some side effects may require medical attention. Patients may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious. Some patients may experience other side effects that are not listed here. This is not a complete list of side effects. What are the most common side effects of treatment with Praxbind? How is Praxbind typically given (administered)? Praxbind is given as an infusion into a vein. This allows thrombin to resume its role in the coagulation process in blood cells. Praxbind binds with Pradaxa with higher affinity than the Pradaxa does to the thrombin. Thrombin is a key element in the coagulation process. What is the mechanism of action? Praxbind is a monoclonal antibody made to reverse Pradaxa, a compound that directly blocks thrombin.
For which conditions is this drug approved? Praxbind® is indicated for patients specifically treated with Pradaxa® (dabigatran etexilate mesylate), an anti-clotting agent, when reversal of the anti-clotting effects of the agent is needed for emergency procedures, life-threatening instances, or uncontrolled bleeding.
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